Test presentation
Serum free light chain (sFLC) quantification is an effective tool in both diagnosis and monitoring, in conjunction with other laboratory and clinical findings (i.e. Serum Protein Electrophoresis, Serum and Urine Immunofixation etc…) for myeloma and related dyscrasias.
The sebia FLC Kappa & sebia FLC Lambda kits allow the measurement of kappa and lambda free light chains in human serum, either using a manual technique or a fully automated on the das AP22 ELITE ELISA processor. This test has been designed to overcome most of the proven analytical issues related to serum free light chains quantitative assays based on nephelometry/turbidimetry techniques (hook effect, high retest rate, short measuring range, lot-to-lot variability, etc…).
It also solves most of the sFLC overestimation shown by historical techniques, giving results with better coherence to the “gold standard” for M-spike quantification: Serum Protein Electrophoresis.