Capillary electrophoresis is a proven technology(1),(2),(3) for hemoglobin disorders screening and provides high quality results.
Sebia CAPILLARYS 3 DBS is the latest generation of instrument dedicated to newborn hemoglobin screening, offering a smooth workflow and excellent analytical features.
The CAPILLARYS 3 DBS instrument is an automated, multitasking capillary electrophoresis instrument using 12 capillaries for multiple simultaneous hands-free electrophoretic separations at high throughput.
The CAPILLARYS 3 DBS enables the analysis of samples from microplate wells and provides fully automated electrophoresis separation, from the dried blood spots on filter paper (Guthrie card) through to the final electrophoretic pattern: sample identification, sample dilution, sample incubation, capillary washing, sample injection into the capillaries, migration, detection, processing of the results, and transfer over the computer interface.
This instrument is an interesting alternative to commonly used technology such as IEF and HPLC for all the laboratories involved in newborn hemoglobin screening, bringing seamless sample traceability, high quality results, and high throughput while offering a reduced hands-on time.
Up to 70 samples/hour, enabling Newborn Screening laboratories to cope with their workload and deliver results to pathologists and clinicians quickly.
From sample punch to result, there is no interruption in the traceability chain, preventing transcription mistakes (e.g. errors from manually entering the sample ID into the analysis software).
8 full 96-well microplates could be analysed in a single run, without any reagent refill – This saves hands on time and lets the lab staff focus on important tasks.
RFID tags for all reagents and Hb AF Control ensure a smooth and efficient reagent management, reducing user intervention.
Sample types: dried blood spot (3.2mm)
With 12 capillaries in parallel, the CAPILLARYS 3 DBS can process a large number of samples and can analyse up to eight 96-well microplates without reagent refill.
CAPI 3 NEONAT Hb 70
* Using PHORESIS Software version 9.40 D
The perfect match for screening hemoglobin disorders in newborns.
IFCC Euromedlab 2021
Sebia booth: #121
Sebia Workshop: EduW22
The perfect match for screening hemoglobin disorders in newborns
IFCC Worldlab 2022
Sebia booth: #72
Sebia Workshop: EduW25
This special Issue related to newborn screening for Sickle Cell disease and other hemoglobinopathies tried to cover the most widely faced challenges in the field of newborn screening for SCD.
(1) Hemoglobinopathies: Current: Practices for Screening, Confirmation and Follow-up – CDC – 2015 https://www.cdc.gov/ncbddd/sicklecell/documents/nbs_hemoglobinopathy-testing_122015.pdf
(2) NHS Sickle Cell and Thalassaemia Screening Programme- 2017 https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/585126/NHS_SCT_Handbook_for_Newborn_Laboratories.pdf
(3) Newborn Screening for Sickle Cell Disease and Other Hemoglobinopathies: A Short Review on Classical Laboratory Methods—Isoelectric Focusing, HPLC, and Capillary Electrophoresis: https://www.mdpi.com/2409-515X/4/4/39
This section contains information intended for wide distribution and may therefore contain product details or information that is not available or valid in your country.
Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.