The most common method to detect A1AT deficiency is protein phenotyping using isoelectric focusing.
The HYDRAGEL 18 A1AT ISOFOCUSING kit used on the HYDRASYS 2 SCAN FOCUSING instrument provides qualitative detection of the different phenotypes of the A1AT in human serum.
The semi-automated HYDRASYS 2 instrument enables migration, immunofixation and direct detection on agarose gels, to obtain A1AT profiles for qualitative analysis.
Phenotyping results in conjunction with clinical findings and other laboratory assays aid in the diagnosis of Alpha 1-antitrypsin deficiency.
100% of concordance with another agarose gel isocelectric focusing and in agreement with the different phenotypes.
Clear band visualization for a reliable interpretation.
Simple step-by-step procedure without membrane transfer for 2.5 hours of turnaround time.
HYDRAGEL 18 A1AT ISOFOCUSING is included in both screening and diagnostic algorithms to provide clinicians with phenotype of A1AT proteins secreted in blood circulation.
The HYDRAGEL 18 A1AT ISOFOCUSING assay is based on the principle of agarose gel isoelectrofocusing followed by immunofixation.
Human serum samples can be used with HYDRAGEL 18 A1AT ISOFOCUSING.
10 gels of 18 tests.
Large menu with high quality results on gel electrophoresis.
IFCC Euromedlab 2021
Sebia booth: #121
Sebia Workshop: EduW22
IFCC Worldlab 2022
Sebia booth: #72
Sebia Workshop: EduW25
Pitfalls and caveats in α1-antitrypsin deficiency testing: a guide for clinicians.
Evaluation of Sebia’s isoelectrofocusing kit for A1AT with HYDRASYS.
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Carefully read the instructions in the reagent package inserts and instrument manuals.