About
The Sebia systems use the principle of capillary electrophoresis (CE) in free solution.
Charged molecules are separated by their electrophoretic mobility at a specific pH in an alkaline buffer.
Separation occurs according to the electrolyte pH and electroosmotic flow. CE has a steady flow, compared to the pumped parabolic flow of the High-Performance Liquid Chromatography technique (HPLC). The steady flow results in narrower peaks and better resolution.
The Sebia capillary electrophoresis instruments are equipped with several parallel capillaries enabling multiple simultaneous analyses and scalable throughput:
Sebia’s Expertise
8000 SEBIA CE instruments running everyday around the world.
Clinical & Analytical performances
- Dynamic separation and high resolution
- Changes to complex and multimolecular profiles
- Quantification of small molecules/post-translational modifications
- Powerful separation technology
- Indisputable quality
- Recognised capillary performance (EEQ, Evaluations etc.)
Operational efficiency
- Turn your main gel routine tests in a fully automated technique (SPE, UPE, IF, Hemoglobin)
- Quick and accurate measurements for diagnosis and monitoring
- Short analysis time and fully automated
- Low waste production
Featured resources on Capillary Electrophoresis
See all resourcesInternational standardization of CDT measurement
IFCC CDT-Working Group standardized the CDT measurement.
Standardisation of the CDT measurement on CAPILLARYS 3 TERA
IFCC Standardisation of the Sebia CDT measurement on CAPILLARYS 3 TERA.
Interview with M. Jean Deenmamode, CDT IFCC Working Group Chair
Interview between Sebia and M. Jean Deenmamode, CDT IFCC Working Group Chair
Carbohydrate-deficient transferring testing: a truly traceable and specific biomarker for chronic alcohol misuse
Article from Jean Deenmamode, IFCC CDT working group chair in CLI magazine.
The simple principles of innovative Capillary electrophoresis testing
Understand in 2 minutes how capillary electrophoresis works, and why it gives such high and clear resolution in lab testing.
Discover how the automation track integration boosted the high potential of CAPILLARYS 3
With this short video report, become aware of all the benefits of partnering with Sebia and integrate your capillary electrophoresis into the lab track automation.
Effects of hemoglobin C, D, E and S traits on measurements of hemoglobin A1c by twelve methods
Hemoglobin C, D Punjab, E or S trait can interfere with hemoglobin A1c (HbA1c) results depending on the method of analysis used. Therefore, it is important to know the limitations of the method used for HbA1c determination.
The impact of red blood cell lifespan on HbA1c measurement
This article reminds the reader of the importance of detecting the Hb variants when measuring HbA1c for the labs and clinicians to better interpret the results and to ensure optimal management of the diabetic patient.
EurA1c trial
The EurA1c trial, organized yearly, investigates the performance of HbA1c assays across countries and manufacturers.
Precision of CAPILLARYS 2 for the Detection of Hemoglobin Variants Based on Their Migration Positions
In this report, we evaluated the use of the capillary electrophoresis (CE) migration position in the CAPILLARYS 2 CE instrument.
Further evaluation of the world health organization international reference reagent for Haemoglobin A2 measurement
This article assesses the performances of the different manufacturers and technologies (HPLC and CE) for Hb A2 measurement using both International Reference Reagent for HbA2 (WHO IRR 89/666) and analysis of three whole blood specimens over a range of HbA2, distributed to 56 laboratories located in 14 different countries.
Multiple Myeloma clinical cases for diagnosis and monitoring according to latest IMWG recommendations
Educational Webinar with Prof. Alessandro Gozzetti, MD, PhD
Performance of Immunotyping vs. Immunofixation for the Detection of Monoclonal Gammopathies
Educational Webinar with Katie Thoren, PhD, Memorial Sloan Kettering Cancer Center
Performance of HbA1c Assays in relation to clinical requirements for its use in diabetes
Educational Webinar with Dr. Cas WEYKAMP
CAPILLARYS 3 DBS – Introductory video
The perfect match for screening hemoglobin disorders in newborns
Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies – MDPI – 2019
This special Issue related to newborn screening for Sickle Cell disease and other hemoglobinopathies tried to cover the most widely faced challenges in the field of newborn screening for SCD.
Early detection of Multiple Myeloma: The importance of serum protein electrophoresis
Educational Webinar with Dr. Julien GUILLEMAUD
Clinical and Operational Aspects of Measuring Hemoglobin A1c by Capillary Electrophoresis
Educational Webinar with David G. Grenache, PhD, D(ABCC)
Chief Scientific Officer, TriCore Reference Laboratories
Modern Approach to Screening for Monoclonal Gammopathies Using Digital Workflows
Educational Webinar with Dr. Mark Zaydman from Washington University School of Medicine in St. Louis, MO
The importance of SPE and A1AT phenotyping for a better AATD patient management
Educational Webinar Pr Simone Scarlata
Hemoglobinopathy Testing: What are the Key Points a Lab Should Consider?
Educational Webinar Dr. Cornelia L. Harteveld from Leiden University Medical Center
Hemoglobinopathy Investigation – The Case for Capillary Electrophoresis
Educational Webinar with Jason EYRE
Challenges in Implementing Capillary Electrophoresis for Immunotyping
Educational Webinar with Dr. Jack Maggiore from Loyola University Medical Center in Chicago, IL
Discover the main applications related to the CDT marker
CDT is a sensitive and specific marker of chronic alcohol abuse, used in several contexts and notably including forensic settings, industries, clinical applications.
AL Amyloidosis: Role of clinical lab in diagnosis and management
Educational Webinar with Prof. Giovanni PALLADINI, PhD
Road-traffic accidents: CDT, a reliable marker for chronic alcohol abuse testing
Educational Webinar with Dr Nadia Maria Porpiglia
Improving the diagnosis of AATD with aid of Serum Protein Electrophoresis
Educational Webinar with Dr. Ilaria Ferrarotti
How External Quality Assessment supports quality improvement in laboratory hemoglobinopathy diagnosis
Educational Webinar with Dr. Barbara De la Salle
Sebia receives U.S. FDA Clearance for the CAPILLARYS 3 DBS devices
The next generation instrument for screening hemoglobin disorders in newborns.
To see or not A1c? HbA1c utilization in light of recent lab guidelines
Educational Webinar with Dr. Matthew C. Wagner
Capillary Electrophoresis for Hemoglobinopathy and Thalassemia Evaluation: A Case-Based Approach
Educational Webinar with Mark R. Girton, MD and Dr. Matthew C. Wagner
CAPILLARYS 3 TERA MC – High Capacity and Flexibility solution
Discover the new CAPILLARYS 3 TERA Features and Performance
Navigating the new normal for A1c analysis: Interpreting recently released clinical guidelines in the lab
The latest ADA guidelines highlight the impact of hemoglobin variants on HbA1c results. Sebia’s A1c assay helps labs meet these standards with confidence.
CAPILLARYS 3 TERA MC testimonial
Watch the video to hear about the experience from one of our CAPILLARYS 3 TERA MC evolution customer.
Upcoming events
See all eventsApr. 11, 2022 Jul. 30, 2025
IFCC Euromedlab 2021
Sebia booth: #121
Sebia Workshop: EduW22
Jun. 27, 2022 Jun. 29, 2022
IFCC Worldlab 2022
Sebia booth: #72
Sebia Workshop: EduW25
May. 22, 2023 May. 24, 2023
IFCC Euromedlab /WorldLab 2023
Sebia booth: #21
Sebia Workshop: EduW15
Apr. 10, 2025 Apr. 12, 2025
European Myeloma Network Meeting – EMN 2025
Sebia booth: #6
May. 19, 2025 May. 21, 2025
IFCC Euromedlab 2025
Sebia booth: #108
Sebia Workshop: EduW15
MINICAP FLEX-PIERCING
The compact and affordable automation of Capillary Electrophoresis.
CAPILLARYS 3 OCTA
Evolution makes the difference.
CAPILLARYS 3 TERA MC
Capillary Electrophoresis solution to meet your high capacity needs.
CAPILLARYS 3 TERA TLA
Connect our flexible electrophoresis instrument on lab automation track.
CAPILLARYS 3 DBS
The high throughput solution for newborn hemoglobin disorders screening.
Serum Protein by Capillary Electrophoresis
High throughput Serum Protein Electrophoresis, with high resolution results.
Urine Protein by Capillary Electrophoresis
High throughput Urine Protein Electrophoresis, with high resolution results.
Serum and Urine Immunotyping
Fully automated monoclonal proteins identification by Capillarys electrophoresis.
Carbohydrate Deficient Transferrin (CDT)
The most reliable chronic alcohol abuse marker.
Hemoglobin disorders screening
The high-resolution method for hemoglobin disorders screening.
Newborn Hemoglobin Disorders Screening
The perfect match for screening hemoglobin disorders in newborns.
This section contains information intended for wide distribution and may therefore contain product details or information that is not available or valid in your country.
Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.