The Sebia systems use the principle of capillary electrophoresis (CE) in free solution.
Charged molecules are separated by their electrophoretic mobility at a specific pH in an alkaline buffer.
Separation occurs according to the electrolyte pH and electroosmotic flow. CE has a steady flow, compared to the pumped parabolic flow of the High-Performance Liquid Chromatography technique (HPLC). The steady flow results in narrower peaks and better resolution.
The Sebia capillary electrophoresis instruments are equipped with several parallel capillaries enabling multiple simultaneous analyses and scalable throughput:
8,000 SEBIA CE instruments running everyday around the world.
Clinical & Analytical performances
The EurA1c trial, organized yearly, investigates the performance of HbA1c assays across countries and manufacturers.
Understand in 2 minutes how capillary electrophoresis works, and why it gives such high and clear resolution in lab testing.
This article assesses the performances of the different manufacturers and technologies (HPLC and CE) for Hb A2 measurement using both International Reference Reagent for HbA2 (WHO IRR 89/666) and analysis of three whole blood specimens over a range of HbA2, distributed to 56 laboratories located in 14 different countries.
In this report, we evaluated the use of the capillary electrophoresis (CE) migration position in the CAPILLARYS 2 CE instrument.
This article reminds the reader of the importance of detecting the Hb variants when measuring HbA1c for the labs and clinicians to better interpret the results and to ensure optimal management of the diabetic patient.
Hemoglobin C, D Punjab, E or S trait can interfere with hemoglobin A1c (HbA1c) results depending on the method of analysis used. Therefore, it is important to know the limitations of the method used for HbA1c determination.
Article from Jean Deenmamode, IFCC CDT working group chair in CLI magazine.
Interview between Sebia and M. Jean Deenmamode, CDT IFCC Working Group Chair
IFCC Standardisation of the Sebia CDT measurement on CAPILLARYS 3 TERA.
IFCC CDT-Working Group standardized the CDT measurement.
Educational Webinar with Katie Thoren, PhD, Memorial Sloan Kettering Cancer Center
Educational Webinar Dr. Cornelia L. Harteveld from Leiden University Medical Center
Educational Webinar with Dr. Cas WEYKAMP
The perfect match for screening hemoglobin disorders in newborns
This special Issue related to newborn screening for Sickle Cell disease and other hemoglobinopathies tried to cover the most widely faced challenges in the field of newborn screening for SCD.
Learn how a Sebia customer utilized our Workflow Service offering and CAPILLARYS 3 instruments to achieved higher throughput and improved workflow.
Educational Webinar with Dr. Julien GUILLEMAUD
Educational Webinar with David G. Grenache, PhD, D(ABCC)
Chief Scientific Officer, TriCore Reference Laboratories
Learn how a Sebia customer gained both clinically and operationally with a simplified IT workflow.
Educational Webinar with Dr. Jack Maggiore from Loyola University Medical Center in Chicago, IL
Educational Webinar with Jason EYRE
CDT is a sensitive and specific marker of chronic alcohol abuse, used in several contexts and notably including forensic settings, industries, clinical applications.
The compact and affordable automation of Capillary Electrophoresis.
Evolution makes the difference.
The power of up to 36 capillaries in one automated high volume workcell.
High throughput Serum Protein Electrophoresis with high resolution results.
High throughput Urine Protein Electrophoresis, with high resolution results.
Fully automated monoclonal proteins identification by Capillarys electrophoresis.
The high-resolution method for hemoglobin disorders screening.
Uncompromized HbA1c Results.
The most reliable chronic alcohol abuse marker.
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Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.